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Getting Started

  • What is VarElect?

    VarElect is a cutting edge Variant Election application for disease/phenotype-dependent gene variant prioritization.  It is an effective and user friendly tool for analyzing genes with variants follow...

  • How does VarElect score gene-phenotype associations?

    Genes receive a relevance score depending (in part) on the weight of each query term that appears in relation to a given gene.  The weight of a term is determined by the frequency it appears in associ...

  • What is an indirect assocation?

    Indirect association between genes and disease are based on shared pathways, interaction networks, paralogy relations, domain-sharing, and mutual publications. An example of an indirect GeneCards-base...

  • What support does VarElect have for WGS?

    VarElect allows phenotype interpretation for non-coding variants sequenced by Whole Genome Sequencing (WGS). This functionality is implemented by leveraging GeneHancer - the regulatory elements (promo...