What is VarElect?

VarElect is a cutting edge Variant Election application for disease/phenotype-dependent gene variant prioritization.  It is an effective and user friendly tool for analyzing genes with variants following Next-Generation Sequencing (“NGS”) experiments. VarElect can rapidly prioritize genes that have been found to have variants according to selected disease/phenotype - gene associations. 

VarElect leverages the rich information within the LifeMap Knowledgebase of GeneCards®, the leading human gene database, MalaCards, the human disease database, LifeMap Discovery®, the regenerative medicine database, and PathCards, the unified human biological pathways database.

Using VarElect you can input a list of dozens, or hundreds of genes with variants, and narrow it down to the top 1-10 genes that are potentially associated with a particular disease, phenotype, or other biological function. VarElect acts jointly on the gene list and phenotype/disease keywords, and produces a list of prioritized, scored, and contextually annotated genes and direct links to supporting evidence and further information. VarElect utilizes the deep LifeMap Knowledgebase to infer direct, as well as indirect, links between genes and phenotypes.